Browsing by Author "Rugarabamu, Sima"
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Item Aedes aegypti abundance, larval indices and risk for dengue virus transmission In Kinondoni district, Tanzania(BMC, 2022) Ngingo, Baraka L; Mboera, Leonard E. G; Chengula, Augustino; Machelle, Ines; Makange, Mariam R; Msolla, Michael; Mwanyika, Gaspary O; Rugarabamu, Sima; Misinzo, GeraldBackground: Tanzania has experienced periodic dengue outbreaks with increased incidence since 2010. However, there is limited information on vector dynamics and transmission risk in most parts of the country. This study was conducted to determine Aedes mosquito abundance, larval indices and dengue virus infection rate as risk indicators for DENV transmission in Kinondoni district, Dar es Salaam, Tanzania. Methods: A cross-sectional study was conducted in three wards of Kinondoni district in Tanzania between Decem- ber 2019 and January 2020. In each ward, three streets were randomly selected for adult and immature mosquito sampling. The adult mosquitoes were collected using Mosquito Magnet traps, while mosquito larvae and pupae were inspected in water-holding containers in the selected household compounds. The detection of dengue virus (DENV) in female Aedes mosquitoes was done using a one-step reverse transcription–polymerase chain reaction (RT–PCR) method. Results: Of the 1416 adult female mosquitoes collected, Ae. aegypti accounted for 16.8% (n = 238). A total of 333 water-holding containers were inspected and 201 (60.4%) had at least an Aedes larvae or pupae. Water-holding containers supporting the breeding of Aedes larvae and pupae included discarded car tires, flowerpots and small and large plastic containers. The overall House Index, Container Index and Breteau Index were 55.1%, 60.4% and 114.2, respectively. None of the 763 female Aedes mosquitoes tested by RT–PCR was found to be infected with DENV. Conclusion: The presence and abundance Ae. aegypti mosquitoes and the large proportion of water-holding con- tainers infested with the mosquito larvae and pupae put residents of Kinondoni district at high risk of DENV trans- mission. Our findings emphasize the need for continuous mosquito vector surveillance and control to prevent the possibility of future DENV outbreaks in Tanzania.Item Circulation of dengue serotype 1 viruses during the 2019 outbreak in Dar es Salaam, Tanzania(Informa UK Limited, trading as Taylor & Francis Group.) Mwanyika, Gaspary O.; Mboera, Leonard E. G.; Rugarabamu, Sima; Makange, Mariam; Sindato, Calvin; Lutwama, Julius J.; Paweska, Janusz T.; Misinzo, GeraldItem Dengue virus infection and associated risk factors in Africa: a systematic review and meta-analysis(MDPI) Mwanyika, Gaspary O.; Mboera, Leonard E. G.; Rugarabamu, Sima; Ngingo, Baraka; Sindato, Calvin; Lutwama, Julius J.; Paweska, Janusz T.; Misinzo, GeraldItem Forty-two years of responding to ebola virus outbreaks in Sub-Saharan Africa: a review(BMJ Global Health) Rugarabamu, Sima; Mboera, Leonard; Rweyemamu, Mark; Mwanyika, Gaspary; Lutwama, Julius; Paweska, Janusz; Misinzo, GeraldItem Forty-two years of responding to ebola virus outbreaks in Sub-Saharan Africa: a review(BMJ Global Health, 2020-01) Rugarabamu, Sima; Mboera, Leonard; Rweyemamu, Mark; Mwanyika, Gaspary; Lutwama, Julius; Paweska, Janusz; Misinzo, GeraldEbola virus disease (EVD) is one of the deadliest haemorrhagic fevers affecting humans and non- human primates. Thirty-four outbreaks have been reported in Africa since it was first recognised in 1976. This review analysed 42 years of EVD outbreaks and identified various challenges and opportunities for its control and prevention in Sub-Saharan Africa.Item Methicillin-resistant staphylococcus aureus contamination and distribution in patient’s care environment at Muhimbili national hospital, Dar es Salaam-Tanzania(BMC) Nkuwi, Emmanuel James; Kabanangi, Fatima; Joachim, Agricola; Rugarabamu, Sima; Majigo, MtebeItem Seroprevalence and associated risk factors of chikungunya, dengue, and zika in eight districts in Tanzania(Elsevier Ltd) Mwanyika, Gaspary O.; Sindato, Calvin; Rugarabamu, Sima; Rumisha, Susan F.; Karimuribo, Esron D.; Misinzo, Gerald; Rweyemamu, Mark M.; Hamid, Muzamil M. Abdel; Haider, Najmul; Vairo, Francesco; Kock, Richard; Mboera, Leonard E.G.