Description:
Background: Urinary bladder carcinoma is one of the common urological malignancies occurring worldwide in both sexes. The males are more affected than female all over the world. The clinico-pathological features of bladder carcinoma and association of tobacco, occupational exposures and chronic infections in the bladder like schistosomiasis as a possible risk factor for has been well described in the literature.
Justification: With approximately 330,000 new cases occurring each year worldwide this has made it an increasingly important international public health problem. There is a need to determine the magnitude of the problem in the tertiary care at KCMC and to evaluate treatment offered to this disease.
Research Methods: Descriptive partly prospective and retrospective cohort study.
The objective of the study which is hospital based was to determine the clinico-pathological features of histologically confirmed bladder carcinoma in patients attending Kilimanjaro Christian Medical Centre (KCMC) in the period from March 2001 and February 2010 and to find out the management modalities being offered at Kilimanjaro Christian Medical Centre (KCMC).
Patients and methods: Patients of newly diagnosed bladder carcinoma treated at Kilimanjaro Christian Medical Centre (KCMC) from March 2001 to February 2010. The 94 newly diagnosed patients were evaluated with respect to age, clinical presentation, cystoscopic findings, histopathological reports and possible etiological factors. Data were collected retrospectively as well as prospective and prospectively updated at the time of discharge from hospital and during follow up in urology out-patient clinic.
Results: Transitional cell carcinoma accounted for majority 53.8% of the bladder carcinoma in studied population and 33.3% (22/66) of patients had superficial (pTa/pT1) while 44/66 (66.7%) patients had muscle invasive (T2–T4) bladder carcinoma.