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Efficacy of crude extract of Aloe secundiflora against Salmonella gallinarum in experimentally infected free-range chickens in Tanzania

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dc.creator Waihenya, R.K.
dc.creator Mtambo, M.M.A.
dc.creator Nkwengulila, Gamba
dc.creator Minga, U.M.
dc.date 2016-04-12T13:03:21Z
dc.date 2016-04-12T13:03:21Z
dc.date 2002
dc.date.accessioned 2021-05-03T13:28:55Z
dc.date.available 2021-05-03T13:28:55Z
dc.identifier Waihenya, R.K., Mtambo, M.M.A., Nkwengulila, G. and Minga, U.M., 2002. Efficacy of crude extract of Aloe secundiflora against Salmonella gallinarum in experimentally infected free-range chickens in Tanzania. Journal of ethnopharmacology, 79(3), pp.317-323.
dc.identifier http://hdl.handle.net/123456789/1478
dc.identifier 10.1016/S0378-8741(01)00397-X
dc.identifier.uri http://hdl.handle.net/123456789/47311
dc.description Full text can be accessed at http://www.sciencedirect.com/science/article/pii/S037887410100397X
dc.description The ethnoveterinary use of Aloe species extract in free-range local chickens against fowl typhoid was investigated. Five-months-old local chickens, free of antibodies against fowl typhoid were used. The chickens were randomly assorted into five groups including pretreated and infected (G1, n=21), infected and untreated (G2, n=21), infected and treated (G3, n=21), untreated and uninfected (G4, n=10) and treated uninfected (G5, n=10). Groups 1, 2 and 3 were inoculated with 5.0×108 c.f.u/ml of Salmonella gallinarum, following which the chickens were monitored for 15 days. There was a delay on the occurrence of the clinical signs and reduced severity of the disease in the Aloe treated chickens (G1 and G3). The mortality rates were 23.8% (5/21) in G1 (pretreated and infected), 42.8% (9/21) in G2 (infected and untreated) and 14.2% (3/21) in G3 (infected and treated). Antibody levels were raised among the infected and untreated group (G2) while they remained relatively low in the Aloe treated groups (G1 and G3). However, there was a sharp increase in the levels of interleukin 6 (IL-6) in the Aloe treated groups (G1 and G3) as compared to the untreated group (G2) until day 9 post-infection. The results of this work indicate that the extract of Aloe secundiflora may be used in the control of fowl typhoid in chickens. Studies to determine the active ingredients of the plant extract are in progress
dc.language en
dc.publisher Elsevier Ireland Ltd
dc.subject Aloe secundiflora
dc.subject Efficacy
dc.subject Salmonella gallinarum
dc.subject Free-range local chickens
dc.title Efficacy of crude extract of Aloe secundiflora against Salmonella gallinarum in experimentally infected free-range chickens in Tanzania
dc.type Journal Article


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