The study was all about agile supply chain practices towards performance of healthcare sector. This research was conducted at Dodoma Municipality in Benjamin Mkapa hospital and Dodoma general hospital. The specific objectives of the study were to assess timely delivery of treatment to the patients on performance of healthcare in Dodoma Municipality, to evaluate integration and coordination of process towards performance of healthcare in Dodoma Municipality, to assess the extent to which quick response to patients enhance performance of healthcare in Dodoma Municipality and to ascertain the effects of agile supply chain practices on performance of healthcare in Dodoma Municipal. Data were collected by using both primary source of data and secondary source of data. Primary data was collected by using questionnaire and interview while the secondary data was collected by using documentary review and the study used the sample size of 236 respondents. Data was analyzed by both qualitative and quantitative analysis. To determine the effects of agile supply chain practices on performance of healthcare logistic regression model was used and Pearson chi-square was used to determine the influence of timely delivery of treatment, integration and coordination of process and quick response to the patients towards performance of healthcare in terms of patient‟s satisfaction. Results indicated that treatment conducted at reasonable time, waiting for registration, ICT uses in healthcare operations, reduction of path flows and quick medical assistance have positive significantly relationship on performance of healthcare in terms of patients satisfaction whereas time to contact medical personnel, effective communication and quick response with change number of patients has insignificant relationship towards patients satisfaction. Results from Pearson chi-square indicated significant relationship between timely delivery of treatment, integration and coordination of process with performance of healthcare in terms of patient‟s satisfaction, whereas quick response to the patients has insignificant relationship with performance of healthcare. The study recommends that the Government should employ adequate number of doctors, nurses, pharmacists and laboratory technicians in order to smoothen the daily operations of public hospitals.