This study aimed at assessing challenges facing quality assurance officers in enhancing quality education in Nyamagana district Mwanza Tanzania. The study was guided by four specific objectives namely; to establish the approaches used by quality assurance officers in enhancing quality education in secondary schools, to examine whether the unavailability of resources can be a challenge in enhancing quality education, to investigate whether lack of training and seminars to quality assurance officers can hinder the enhancement of quality education in secondary schools, and to explore whether the involvement of stakeholders in education can hinder the enhancement of quality education in secondary schools.Thestudy employed qualitative research approach and used descriptive research design. The data was collected through questionnaire and interview methods. The data was collected from quality assurance officers who work at the zonal quality assurance office in Nyamagana District. The staff has 25 quality assurance officers and the data was collected from 16 out of them.The study found that quality assurance officers face challenges such as lack of enough resources like human resources, financial resources and physical resources.Furthermore, the study indicated that quality assurance officers lack seminars and for that case they fail to help teachers hence hinder the enhancement of quality education. It wasalso stipulated that the approaches used are not well implemented due to different challenges in the process. The study suggested that for quality assurance to enhance quality education, they need to be equipped with enough resources to enable them work effectively. The government also should make sure that quality assurance officers are given enough seminars to help them be competent and up to date