This study highlights the costs and benefits of indigenous beef cattle fattening schemes in Shinyanga Urban and Kishapu Districts in Tanzania. Specifically, in this study the net profit (NP) for fatteners between beef cattle fattening schemes has been determined. The schemes were divided into two main categories, scheme 1 in which the animals were fed on cottonseed hulls (CSHL) based diets and scheme 2 on cottonseed cake (CSC) based diets. The survey was carried out using a sample of 144 respondents. The tools for data collec- tion were structured questionnaire, interview, personal observation, communication, documentary reviews (e.g. from internet, libraries) and key informants. Data were analysed using descriptive statistics and quanti- tative statistics and standard procedure of the association of official analytical chemists. Results show that the positive net profit was relatively higher in scheme 2 (Tanzanian shilling (TAS) 119512.87 / USD 76.03 per fed animal per quarter a year) than that in scheme 1 (TAS 92993, 90 / USD 59.17 per fed animal per quarter a year). This implies that the fattening business is more feasible, profitable and efficient for sustain- able implementation in scheme 2. Furthermore, the average daily gains (ADG) of 1.5, 1.3 and 1.0 for Tan- zania Short Horn Zebu (TSHZ) males, steers and females were higher than the 1.2, 1.0 and 0.9 for TSHZ males, steers and females in scheme 1, respectively. Additionally, the feed conversion ratios (FCRs) of about 5.0, 5.5, 6.3 for TSHZ males, steers and females in scheme 2 were lower than 7.2, 8.6, 8.6 for TSHZ males, steers and females in scheme 1. Therefore, scheme 2 was economically feasible, profitable and therefore is recommended for implementation and monetary support for improved income, livelihoods, poverty reduction and commercialisation of the beef industry.