Using giant African pouched rats to detect tuberculosis in human sputum samples: 2010 findings

Mahoney, A.M; Weetjens, B.J; Cox, C; Beyene, N; Mgode, G; Jubitana, M; Kuiper, D; Kazwala, R; Mfinanga, G.S; Durgin, A; Poling, A

dc.creator	Mahoney, A.M
dc.creator	Weetjens, B.J
dc.creator	Cox, C
dc.creator	Beyene, N
dc.creator	Mgode, G
dc.creator	Jubitana, M
dc.creator	Kuiper, D
dc.creator	Kazwala, R
dc.creator	Mfinanga, G.S
dc.creator	Durgin, A
dc.creator	Poling, A
dc.date	2017-04-04T12:17:17Z
dc.date	2017-04-04T12:17:17Z
dc.date	2011-07-17
dc.date.accessioned	2022-10-25T08:50:13Z
dc.date.available	2022-10-25T08:50:13Z
dc.identifier	1937- 8688
dc.identifier	https://www.suaire.sua.ac.tz/handle/123456789/1378
dc.identifier.uri	http://hdl.handle.net/123456789/89934
dc.description	Pan African Medical Journal 2011, Vol 9:28
dc.description	Giant African pouched rats previously have detected tuberculosis (TB) in human sputum samples in which the presence of TB was not initially detected by smear microscopy. Operant conditioning principles were used to train these rats to indicate TB-positive samples. In 2010, rats trained in this way evaluated 26,665 sputum samples from 12,329 patients. Microscopy performed at DOTS centers found 1,671 (13.6%) of these patients to be TB-positive. Detection rats identified 716 additional TB-positive patients, a 42.8% increase in new-case detection. These previously unreported data, which extend to over 20,000 the number of patients evaluated by pouched rats in simulated second-line screening, suggest that the rats can be highly valuable in that capacity.
dc.format	application/pdf
dc.language	en
dc.subject	Giant African pouched
dc.subject	Tuberculosis
dc.subject	Human sputum
dc.subject	TB
dc.title	Using giant African pouched rats to detect tuberculosis in human sputum samples: 2010 findings
dc.type	Article