Journal of Continuing Education and Extension 2013, Vol. 4(1): pp184-196A study was conducted to assess community perception towards male circumcision and HIV prevention in Makete District. A cross-sectional research design was used employing quantitative and qualitative for data collection. Quantitative data were collected using a questionnaire administered to 420 respondents; while qualitative data were collected using a checklist with questions administered to key informants and focus group discussants. The prevalence rate for HIVIAIDS was found to be 11% determined using secondary data from Makete district Hospital. It was noted that 59.7% of the respondents had a negative perception towards male circumcision while 32.7% had a positive perception. Positive perceptions of men and women were found to be an important aspect towards male circumcision. It was also noted that cultural factors hinder men to opt for male circumcision. The need for including women in the campaign towards male circumcision was found to influence male circumcision of their sexual partner. These findings lead to the conclusion that in order to have an effective HIVIAIDS prevention programs, a combination of approaches is required. Nonetheless, male circumcision should never replace other known methods such as use of condom for HIV prevention.