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Treponema infection associated with genital ulceration in wild baboons

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dc.creator Knauf, S
dc.creator Batamuzi, E. K
dc.creator Mlengeya, T
dc.creator Kilewo, M
dc.creator Lejora, I. A. V
dc.creator Nordhoff, M
dc.creator Ehlers, B
dc.creator Harper, K. N
dc.creator Fyumagwa, R
dc.creator Hoare, R
dc.creator Failing, K
dc.creator Wehrend, A
dc.creator Kaup, F. J
dc.creator Leendertz, F. H
dc.creator Mätz-Rensing, K
dc.date 2022-05-17T10:03:00Z
dc.date 2022-05-17T10:03:00Z
dc.date 2012
dc.date.accessioned 2022-10-25T08:50:41Z
dc.date.available 2022-10-25T08:50:41Z
dc.identifier 292-303
dc.identifier https://www.suaire.sua.ac.tz/handle/123456789/4143
dc.identifier.uri http://hdl.handle.net/123456789/90523
dc.description The authors describe genital alterations and detailed histologic findings in baboons naturally infected with Treponema pallidum. The disease causes moderate to severe genital ulcerations in a population of olive baboons (Papio hamadryas anubis) at Lake Manyara National Park in Tanzania. In a field survey in 2007, 63 individuals of all age classes, both sexes, and different grades of infection were chemically immobilized and sampled. Histology and molecular biological tests were used to detect and identify the organism responsible: a strain similar to T pallidum ssp pertenue, the cause of yaws in humans. Although treponemal infections are not a new phenomenon in nonhuman primates, the infection described here appears to be strictly associated with the anogenital region and results in tissue alterations matching those found in human syphilis infections (caused by T pallidum ssp pallidum), despite the causative pathogen’s greater genetic similarity to human yaws-causing strains.
dc.format application/pdf
dc.language en
dc.publisher The American College of Veterinary Pathologists
dc.subject Treponema pallidum
dc.subject Genital
dc.subject Histology
dc.subject Immunohistochemistry
dc.subject Nonhuman primate
dc.subject Olive baboon (Papio hamadryas anubis)
dc.subject Sexually transmitted disease
dc.subject Syphilis
dc.title Treponema infection associated with genital ulceration in wild baboons
dc.type Article


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