Porcine reproductive and respiratory syndrome virus entry into the porcine macrophage

Breedam, W. V.; Delputte, P. L.; Van Gorp, H.; Misinzo, G.; Vanderheijden, N.; Duan, X.; Nauwynck, H. J.

dc.creator	Breedam, W. V.
dc.creator	Delputte, P. L.
dc.creator	Van Gorp, H.
dc.creator	Misinzo, G.
dc.creator	Vanderheijden, N.
dc.creator	Duan, X.
dc.creator	Nauwynck, H. J.
dc.date	2017-06-24T14:04:26Z
dc.date	2017-06-24T14:04:26Z
dc.date	2010
dc.date.accessioned	2022-10-25T08:51:39Z
dc.date.available	2022-10-25T08:51:39Z
dc.identifier	https://www.suaire.sua.ac.tz/handle/123456789/1719
dc.identifier.uri	http://hdl.handle.net/123456789/91600
dc.description	Journal of General Virology 2010, Vol. 91: 1659–1667
dc.description	Porcine reproductive and respiratory syndrome virus (PRRSV) emerged in the late 1980s and rapidly became one of the most significant viral pathogens in the swine industry. In vivo, the virus shows a very narrow cell tropism and targets specific subsets of porcine macrophages. The entry of PRRSV into its host cell is the first crucial step in infection and has been the focus of many fundamental studies. This review provides a comprehensive overview of the current knowledge on PRRSV entry into the porcine macrophage, covering virus binding, internalization and genome release, and integrates these findings into a general model of the entry process.
dc.format	application/pdf
dc.language	en
dc.publisher	Journal of General Virology
dc.subject	Syndrome virus
dc.subject	Porcine macrophage
dc.subject	Porcine reproductive
dc.subject	PRRSV
dc.subject	Arteriviridae
dc.subject	Nidovirales
dc.title	Porcine reproductive and respiratory syndrome virus entry into the porcine macrophage
dc.type	Article