African 2, a clonal complex of mycobacterium bovis epidemiologically important in East Africa

Stefan, Berg, M; Borna, Müller; Elena, Hailu; Benon, Asiimwe; Kristin, Kremer; James, Dale M; Beatrice, Boniotti; Sabrina, Rodriguez; Markus, Hilty; Leen, Rigouts; Rebuma, Firdessa; Adelina, Machado; Custodia, Mucavele; Bongo, Nare R. N; Bruchfeld, Judith; Boschiroli, Laura; Müller, Annélle; Sahraoui, Naima; Pacciarini, Maria; Cadmus, Smeoni; Joloba, Moses; Joloba, Moses; Soolingen, Dick v; Michel, Anita L.; Djønne, Berit; Aranaz, Alicia; Zinsstag, Jakob; Portaels, Françoise; Kazwala, Rudovick; Källenius, Gunilla; Hewinson, Glyn; Aseffa, Abraham; Gordon, Stephen V.; Smith, Noel H.; Garcia-Pelayo, M. Carmen

dc.creator	Stefan, Berg, M
dc.creator	Borna, Müller
dc.creator	Elena, Hailu
dc.creator	Benon, Asiimwe
dc.creator	Kristin, Kremer
dc.creator	James, Dale M
dc.creator	Beatrice, Boniotti
dc.creator	Sabrina, Rodriguez
dc.creator	Markus, Hilty
dc.creator	Leen, Rigouts
dc.creator	Rebuma, Firdessa
dc.creator	Adelina, Machado
dc.creator	Custodia, Mucavele
dc.creator	Bongo, Nare R. N
dc.creator	Bruchfeld, Judith
dc.creator	Boschiroli, Laura
dc.creator	Müller, Annélle
dc.creator	Sahraoui, Naima
dc.creator	Pacciarini, Maria
dc.creator	Cadmus, Smeoni
dc.creator	Joloba, Moses
dc.creator	Joloba, Moses
dc.creator	Soolingen, Dick v
dc.creator	Michel, Anita L.
dc.creator	Djønne, Berit
dc.creator	Aranaz, Alicia
dc.creator	Zinsstag, Jakob
dc.creator	Portaels, Françoise
dc.creator	Kazwala, Rudovick
dc.creator	Källenius, Gunilla
dc.creator	Hewinson, Glyn
dc.creator	Aseffa, Abraham
dc.creator	Gordon, Stephen V.
dc.creator	Smith, Noel H.
dc.creator	Garcia-Pelayo, M. Carmen
dc.date	2022-05-17T09:31:42Z
dc.date	2022-05-17T09:31:42Z
dc.date	2011
dc.date.accessioned	2022-10-25T08:51:42Z
dc.date.available	2022-10-25T08:51:42Z
dc.identifier	0021-9193
dc.identifier	https://www.suaire.sua.ac.tz/handle/123456789/4140
dc.identifier.uri	http://hdl.handle.net/123456789/91666
dc.description	We have identified a clonal complex of Mycobacterium bovis isolated at high frequency from cattle in Uganda, Burundi, Tanzania, and Ethiopia. We have named this related group of M. bovis strains the African 2 (Af2) clonal complex of M. bovis. Af2 strains are defined by a specific chromosomal deletion (RDAf2) and can be identified by the absence of spacers 3 to 7 in their spoligotype patterns. Deletion analysis of M. bovis isolates from Algeria, Mali, Chad, Nigeria, Cameroon, South Africa, and Mozambique did not identify any strains of the Af2 clonal complex, suggesting that this clonal complex of M. bovis is localized in East Africa. The specific spoligotype pattern of the Af2 clonal complex was rarely identified among isolates from outside Africa, and the few isolates that were found and tested were intact at the RDAf2 locus. We conclude that the Af2 clonal complex is localized to cattle in East Africa. We found that …
dc.format	application/pdf
dc.language	en
dc.publisher	American Society for Microbiology
dc.subject	Mycobacterium bovis
dc.subject	East Africa
dc.title	African 2, a clonal complex of mycobacterium bovis epidemiologically important in East Africa
dc.type	Article