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Widespread Treponema pallidum Infection in Nonhuman Primates, Tanzania.

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dc.creator Chuma, I. S
dc.creator Batamuzi, E. K.
dc.creator Collins, D. A.
dc.creator Fyumagwa, R. D.
dc.creator Hallmaier-Wacker, L. K.
dc.creator Kazwala, R. R.
dc.creator Keyyu, J. D.
dc.creator Lejora, I. A.
dc.creator Lipende, I. F.
dc.creator Lüert, S.
dc.creator Paciência, F. M.D.
dc.creator Piel, A.
dc.creator Stewart, F. A.
dc.creator Zinner, D.
dc.creator Roos, C.
dc.creator Knau, S.
dc.date 2018-06-14T06:41:57Z
dc.date 2018-06-14T06:41:57Z
dc.date 2018
dc.date.accessioned 2022-10-25T08:52:06Z
dc.date.available 2022-10-25T08:52:06Z
dc.identifier 1080-6040
dc.identifier https://www.suaire.sua.ac.tz/handle/123456789/2357
dc.identifier.uri http://hdl.handle.net/123456789/92217
dc.description Emerging Infectious Disease .Vol. 24, No. 6—June 2018
dc.description We investigated Treponema pallidum infection in 8 nonhuman primate species (289 animals) in Tanzania during 2015–2017. We used a serologic treponemal test to detect antibodies against the bacterium. Infection was further confirmed from tissue samples of skin-ulcerated animals by 3 independent PCRs (polA, tp47, and TP_0619). Our findings indicate that T. pallidum infection is geographically widespread in Tanzania and occurs in several species (olive baboons, yellow baboons, vervet monkeys, and blue monkeys). We found the bacterium at 11 of 14 investigated geographic locations. Anogenital ulceration was the most common clinical manifestation; orofacial lesions also were observed. Molecular data show that nonhuman primates in Tanzania are most likely infected with T. pallidum subsp. pertenue–like strains, which could have implications for human yaws eradication.
dc.format application/pdf
dc.language en
dc.publisher centers for disease control and prevention.
dc.subject Treponema.
dc.subject Infection.
dc.subject Primates.
dc.subject Tanzania.
dc.subject Species.
dc.subject Pallidum infection.
dc.title Widespread Treponema pallidum Infection in Nonhuman Primates, Tanzania.
dc.type Article


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