"Gairovirus,anovelarena virusof the widespread Mastomys natalensis: genetically divergent,but ecologically similar to Lassa and Morogoro viruses

Gryseels, Sophie; Rieger, Toni; Oestereich, Lisa; Cuypers, Bart; Borremans, Benny; Makundi, Rhodes; Leirs, Herwig; Günther, Stephan; Goüy de Bellocq, Joëlle

dc.creator	Gryseels, Sophie
dc.creator	Rieger, Toni
dc.creator	Oestereich, Lisa
dc.creator	Cuypers, Bart
dc.creator	Borremans, Benny
dc.creator	Makundi, Rhodes
dc.creator	Leirs, Herwig
dc.creator	Günther, Stephan
dc.creator	Goüy de Bellocq, Joëlle
dc.date	2016-12-06T06:27:37Z
dc.date	2016-12-06T06:27:37Z
dc.date	2015
dc.date.accessioned	2022-10-25T08:52:26Z
dc.date.available	2022-10-25T08:52:26Z
dc.identifier	https://www.suaire.sua.ac.tz/handle/123456789/1085
dc.identifier.uri	http://hdl.handle.net/123456789/92551
dc.description	Despite itsnearpan-Africanrange,theNatalmultimammatemouse, Mastomysnatalensis, carriesthe human pathogenLassavirusonlyinWestAfrica,whiletheseeminglynon-pathogenicarenaviruses Mopeia, Morogoro,andLunahavebeendetectedinthissemi-commensalrodentinMozambique/ Zimbabwe,TanzaniaandZambia,respectively.Here,wedescribeanovelarenavirusin M. natalensis from Gairo districtofcentralTanzania,forwhichweproposethename “Gairo virus”. Surprisingly,thevirusis not closelyrelatedwithMorogorovirusthatinfects M. natalensis only 90kmsouthofGairo,butclusters phylogeneticallywithMobala-likevirusesthatinfectnon-M. natalensis host speciesinCentralAfrican RepublicandEthiopia.Despitetheevolutionarydistance,Gairovirussharesbasicecologicalfeatures with theother M. natalensis-borne virusesLassaandMorogoro.Ourdatashowthat M. natalensis, carrying distantlyrelatedviruseseveninthesamegeographicalarea,isapotentreservoirhostfora varietyofarenaviruses.
dc.format	application/pdf
dc.language	en
dc.publisher	ElsevierInc
dc.subject	Arenavirus
dc.subject	Mastomys natalensis
dc.subject	Virology
dc.subject	Phylogeny
dc.subject	Ecology
dc.subject	Zoonotic infections
dc.subject	Hemorrhagic fevers
dc.subject	Tanzania
dc.title	"Gairovirus,anovelarena virusof the widespread Mastomys natalensis: genetically divergent,but ecologically similar to Lassa and Morogoro viruses
dc.type	Article