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Immunohistochemical detection of Mycoplasma mucoid mucoid small colony type in lungs of slaughtered cattle at Morogoro slaughterhouse, Tanzania

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dc.creator Malago, J. J.
dc.creator Mlay, J. D.
dc.date 2018-06-17T10:19:35Z
dc.date 2018-06-17T10:19:35Z
dc.date 2015
dc.date.accessioned 2022-10-25T08:53:46Z
dc.date.available 2022-10-25T08:53:46Z
dc.identifier https://www.suaire.sua.ac.tz/handle/123456789/2369
dc.identifier.uri http://hdl.handle.net/123456789/94126
dc.description Tanzania Veterinary Journal
dc.description Diagnosis of contagious bovine pleuropneumonia (CBPP) in carrier animals remains to be a challenge in developing countries partly because of lack of diagnostic tools that can detect asymptomatic animals. As a result many apparently healthy animals pose a potential impending epidemic in periods of stress. We examined condemned lungs with CBPP-like lesions from apparently healthy slaughtered animals to confirm presence of the disease in these animals. A total of 13 lungs collected at abattoir were examined immunohistochemically using 3H12 and 6E3 monoclonal antibodies against Mycoplasma mycoides mycoides (MmmSC), the causative agent of CBPP. Both 3H12 and 6E3 antibodies detected the MmmSC antigens in all the 13 lungs in bronchial, bronchiolar and alveolar epithelia, bronchial glands, bronchial cartilage, and in alveoli. We conclude that CBPP is still present in various places of Tanzania, posing a threat to livestock production and that immunohistochemistry can be an efficient diagnostic method to confirm presence of the disease in asymptomatic healthy animals passed for slaughter.
dc.format application/pdf
dc.language en
dc.publisher Tanzania Veterinary Journal
dc.subject CBPP
dc.subject Cattle
dc.subject Monoclonal antibody
dc.subject Lung parenchyma
dc.subject MmmSC antigens
dc.subject Immunohistochemistry
dc.title Immunohistochemical detection of Mycoplasma mucoid mucoid small colony type in lungs of slaughtered cattle at Morogoro slaughterhouse, Tanzania
dc.type Article


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