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Modeling the Dynamics of Rabies Transmission with Vaccination and Stability Analysis

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dc.creator Ega, Tesfaye Tadesse
dc.creator Luboobi, Livingstone S.
dc.creator Kuznetsov, Dmitry
dc.date 2019-05-17T10:41:58Z
dc.date 2019-05-17T10:41:58Z
dc.date 2015-10-09
dc.date.accessioned 2022-10-25T09:15:46Z
dc.date.available 2022-10-25T09:15:46Z
dc.identifier 2328-5613
dc.identifier doi: 10.11648/j.acm.20150406.13
dc.identifier http://dspace.nm-aist.ac.tz/handle/123456789/73
dc.identifier.uri http://hdl.handle.net/123456789/94587
dc.description Research Article published by Science Publishing Group
dc.description In this paper we formulate a deterministic mathematical model for the transmission dynamics of rabies in human and animal within and around Addis Ababa, Ethiopia. Our model involves vaccination program for dog population. The basic reproduction number and effective reproduction numbers are computed and the results are entirely depending on the parameters of dog population, which shows the responsibility of dog population for human and livestock infection. For a specified set of values of parameters as deduced from the data provided by Ethiopian Public Health Institute of Addis Ababa, the basic reproduction number 0 R and the effective reproduction number e R works out to be 2 and 1.6 respectively, which indicates the disease will be endemic. The numerical simulation of reproduction ratio shows that the combination of vaccination, culling of stray dogs and controlling annual crop of new born puppies are the best method to control rabies transmission within and around Adds Ababa. The disease - free equilibrium 0 e is computed. When the effective reproduction number 1 e R < it is proved to be globally asymptotically stable in the feasible region F . When 1 e R > there exists one endemic equilibrium point which is locally asymptotically stable.
dc.format application/pdf
dc.language en_US
dc.publisher Science Publishing Group
dc.subject Rabies
dc.subject Endemic
dc.title Modeling the Dynamics of Rabies Transmission with Vaccination and Stability Analysis
dc.type Article


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