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Mathematical model for the effects of treatment and vaccination controls on the dynamics of rotavirus disease with reference to Uganda

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dc.creator Namawejje, Hellen
dc.creator Luboobi, Livingstone S.
dc.creator Kuznetsov, Dmitry
dc.creator Wobudeya, Eric
dc.date 2020-03-17T06:36:17Z
dc.date 2020-03-17T06:36:17Z
dc.date 2014
dc.date.accessioned 2022-10-25T09:15:49Z
dc.date.available 2022-10-25T09:15:49Z
dc.identifier 1927-5307
dc.identifier http://dspace.nm-aist.ac.tz/handle/123456789/639
dc.identifier.uri http://hdl.handle.net/123456789/94631
dc.description This research article published by SCIK Publishing Corporation, 2014
dc.description In this paper, while Rotavirus has been a recognised disease for a long time in developing countries like Uganda, the control of this endemic disease is still a challenge. We formulated a mathematical model for the dynamics of Rotavirus disease with both treatment and vaccination. The equilibrium points are determined. The disease free equilibrium points are shown to be locally and globally asymptotically stable. We analyzed different reproduction numbers at different doses of vaccination with treatment. Numerical results indicate that rotavirus can be reduced when one or both interventions are implemented. The study recommends that children should always be treated and also complete all their doses of rotavirus vaccines so as to reduce severe infections.
dc.format application/pdf
dc.language en
dc.publisher SCIK Publishing Corporation
dc.subject Effective reproduction numbers
dc.subject Endemic disease
dc.title Mathematical model for the effects of treatment and vaccination controls on the dynamics of rotavirus disease with reference to Uganda
dc.type Article


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