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Understanding the persistence of plague foci in Madagascar.

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dc.creator Andrianaivoarimanana, Voahangy
dc.creator Kreppel, Katharina
dc.creator Elissa, Nohal
dc.creator Duplantier, Jean-Marc
dc.creator Carniel, Elisabeth
dc.creator Rajerison, Minoarisoa
dc.creator Jambou, Ronan
dc.date 2020-01-23T09:34:40Z
dc.date 2020-01-23T09:34:40Z
dc.date 2013-11-01
dc.date.accessioned 2022-10-25T09:20:44Z
dc.date.available 2022-10-25T09:20:44Z
dc.identifier 24244760
dc.identifier doi: 10.1371/journal.pntd.0002382
dc.identifier http://dspace.nm-aist.ac.tz/handle/123456789/535
dc.identifier.uri http://hdl.handle.net/123456789/95190
dc.description Research Article published by PLOS Neglected Tropical Diseases, Volume 7, Issue 11, November 2013
dc.description Plague, a zoonosis caused by Yersinia pestis, is still found in Africa, Asia, and the Americas. Madagascar reports almost one third of the cases worldwide. Y. pestis can be encountered in three very different types of foci: urban, rural, and sylvatic. Flea vector and wild rodent host population dynamics are tightly correlated with modulation of climatic conditions, an association that could be crucial for both the maintenance of foci and human plague epidemics. The black rat Rattus rattus, the main host of Y. pestis in Madagascar, is found to exhibit high resistance to plague in endemic areas, opposing the concept of high mortality rates among rats exposed to the infection. Also, endemic fleas could play an essential role in maintenance of the foci. This review discusses recent advances in the understanding of the role of these factors as well as human behavior in the persistence of plague in Madagascar.
dc.format application/pdf
dc.language en
dc.publisher PLOS Neglected Tropical Diseases
dc.subject Research Subject Categories::NATURAL SCIENCES
dc.title Understanding the persistence of plague foci in Madagascar.
dc.type Article


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