| dc.creator |
Wilson, Elihuruma |
|
| dc.creator |
Chacha, Musa |
|
| dc.creator |
Omolo, Justin |
|
| dc.date |
2021-02-18T11:27:45Z |
|
| dc.date |
2021-02-18T11:27:45Z |
|
| dc.date |
2015-01-06 |
|
| dc.date.accessioned |
2022-10-25T09:21:02Z |
|
| dc.date.available |
2022-10-25T09:21:02Z |
|
| dc.identifier |
https://doi.org/10.9734/EJMP/2015/14950 |
|
| dc.identifier |
https://dspace.nm-aist.ac.tz/handle/20.500.12479/1125 |
|
| dc.identifier.uri |
http://hdl.handle.net/123456789/95376 |
|
| dc.description |
This research article published European Journal of Medicinal Plants, 2015 |
|
| dc.description |
Aim: To screen for the anti-mycobacterial activity of Canthium crassum and Sterculia quinqueloba using two mycobacteria species the Mycobacteria madagascariense and Mycobacteria indicuspranii.
Study Design: In vitro assay of anti-mycobacterial assay was done using 96-well micro-dilution method.
Place and Duration of Study: School of Life Science and Bioengineering, Nelson Mandela African Institution of Science and Technology, Arusha, Tanzania, from April 2014 to June 2014.
Methodology: 96-well-microtitre serial micro-dilution method was used to determine anti-mycobacteria activity to plant extracts.
Results: All extracts exhibited anti-mycobacterial activity to both mycobacteria tested. The minimum inhibition concentration (MIC) ranged from 0.39 – 12.5 mg/mL, with ethyl acetate leaf extract of S. quinqueloba being the most active extracts with MIC value of 0.39 mg/mL against Mycobacteria madagascariense (MM) and 0.78 mg/mL against Mycobacteria indicuspranii (MIP). Petroleum ether and ethyl acetate leaf extract of C. crassum also gave MIC value of 0.78 mg/mL against MM and MIP.
Conclusion: Findings from the present study showed that both plants exhibited activity against mycobacterium species tested. These plants may therefore serve as a source for new ant-mycobacterium drugs worth further studies including isolation and identification of the active compounds. |
|
| dc.format |
application/pdf |
|
| dc.language |
en |
|
| dc.publisher |
European Journal of Medicinal Plants |
|
| dc.subject |
Anti-mycobacterial |
|
| dc.subject |
Canthium crassum |
|
| dc.subject |
Sterculia quinqueloba |
|
| dc.title |
In vitro Antimycobacterial Activity of Sterculia quinqueloba (Garcke) K. Schumand Canthium crassum Hiern |
|
| dc.type |
Article |
|