This research article was published by Hindawi, 2021Concrete structures suffer serious deterioration under a corrosive environment. Consequently, the service life of these concrete structures is decreased and deteriorates under combined attack of sulphate and chlorides. Most studies confined on single deteriorating factor such as sulphate attack only or chloride attack only but the current study focused on the influence of natural pumice (NP) and natural scoria (NS) on the strength performance of concrete exposed to the combined attack of sulphate and chloride. Portland cement (PLC) was replaced with NP or NS at a substitution level of 10%. Concrete samples were cured in water for the curing period of 28 days. Afterwards, the specimens were immersed in 5% sodium sulphate (Na2SO4), 5% sodium chloride (NaCl), and combined sodium sulphate and chloride solutions for additional curing of 28, 56, and 90 days. /e results were compared between concrete mixes with NP or NS and control mix (CT) with PLC. /e effects of sulphate, chloride, and combined sulphate and chloride were evaluated in terms of change in weight, variation in compressive strength, and degree of damage. Conclusively, the application of NP and NS has extraordinary potential to be utilized as a cementitious material in concrete to increase the resistance against aggressive salts.