Modelling the Effect of Screening on the Spread of HIV Infection in a Population with Variable Inflow of Infective Immigrants

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Scientific Research

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This paper examines the combined effects of screening and variable inflow of infective immigrants on the spread of HIV/AIDS (human immunodeficiency virus/acquired immune deficiency syndrome) in a population of varying size. A nonlinear deterministic mathematical model for the problem is proposed and analysed qualitatively using the stability theory of differential equations. The results show that the reproductive number R0 >1 as the rate of inflow of infective immigrants increases leading to persistence of the disease in the population. However, the presence of screening greatly reduces the spread of HIV/AIDS. Numerical simulation of the model is implemented to investigate the sensitivity of certain key parameters on the spread of the disease.

Keywords

Human immunodeficiency virus/acquired immune deficiency syndrome, Screening, Infective immigrants, Reproductive number, Stability analysis, Numerical simulation

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