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Research on vegetable oil for biofuels in Africa and Asia has focused mainly on Jatropha curcas while other potential oil bearing plants have received little attention. Vegetable oil production potential for five oil bearing plant species namely: Aleurites moluccana, Croton megalocarpus, Jatropha curcas, Moringa oleifera and Pachira glabra were investigated. Nuts and seeds of the plants were collected from the wild and their potential for vegetable oil production assessed in terms of seed/nut acreage yield, seed/nut oil content, harvesting requirement, and upstream processing before vegetable oil recovery. All five varieties were found to contain acceptable but different oil content ranging from 20 to 33% w/w, and seed/nut acreage yield of 3 t ha−1 y−1 to 12.5 t ha−1 y−1. Upstream processing was needed for A. moluccana to break open nuts to release the kernel, and dehulling for both C. megalocarpus and J. curcas to release the seeds, before extracting the vegetable oil, while the seeds of both M. oleifera and P. glabra did not need upstream processing. The Multi-criteria Decision Analysis ranked C. megalocarpus as the plant with the highest vegetable oil production potential of 1.8 t ha−1 y−1 followed by M. oleifera, J. curcas (1 t ha−1 y−1), A. moluccana, and P. glabra. The analysis underlines the need for more studies on C. megalocarpus and M. oleifera for biofuel production in Africa and other regions.