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Crystallization and preliminary X-ray analysis of the human c-H-ras-oncogene product p21 complexed with GTP analogues

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dc.creator Scherer, Anna
dc.creator John, Jasson
dc.creator Linke, Rosita
dc.creator Goody, Roger S.
dc.creator Wittinghofer, Alfred
dc.creator Pai, Emil F.
dc.creator Homes, K. C.
dc.date 2016-07-14T20:56:05Z
dc.date 2016-07-14T20:56:05Z
dc.date 1989-03
dc.date.accessioned 2021-05-03T13:29:43Z
dc.date.available 2021-05-03T13:29:43Z
dc.identifier Scherer, A., John, J., Linke, R., Goody, R.S., Wittinghofer, A., Pai, E.F. and Holmes, K.C., 1989. Crystallization and preliminary X-ray analysis of the human cH-ras-oncogene product p21 complexed with GTP analogues. Journal of molecular biology, 206(1), pp.257-259.
dc.identifier http://hdl.handle.net/20.500.11810/3223
dc.identifier 10.1016/0022-2836(89)90540-8 · Source: PubMed
dc.identifier.uri http://hdl.handle.net/20.500.11810/3223
dc.description Full text can be accessed at http://www.sciencedirect.com/science/article/pii/0022283689905408
dc.description The catalytic domain (amino acid residues 1 to 166) of the human ras-oncogene product p21 complexed with the GTP analogues beta,gamma-imido-GTP (GMPPNP), beta,gamma-methylene-GTP (GMPPCP), and guanosine-5'-(gamma-thiotriphosphate) (GTP gamma S) have been been crystallized. Crystals of the GMPPNP and GMPPCP complexes are well suited for high resolution X-ray crystallography. They belong to space group P3(1)21 (or its enantiomorph P3(2)21) with unit cell axes a=b=40.3 A and c = 162.2 A.
dc.language en
dc.publisher Elsevier
dc.title Crystallization and preliminary X-ray analysis of the human c-H-ras-oncogene product p21 complexed with GTP analogues
dc.type Journal Article


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