Agricultural development in developing countries is challenged by weak innovation systems and lack of innovation capacities among key actors. Integration of agricultural innovation perspectives and value chain approach for development have made the interaction between a wide range of actors of innovation to become more complex demanding different sets of knowledge, environment and incentives. The traditional homogeneous intermediary layer of agricultural extension appeared to be ineffective to this situation. As a result the majority of smallholder farmers are facing exclusion from participating in supplying the long value chains. In countries characterized by mature innovation systems, a specialized innovation-brokering role emerged as an alternative to deal with innovation challenges in agricultural sectors (market and system failures). This study, using a case study approach, intended to offer empirical evidence of the roles of innovation brokerage implemented on cassava value chain by NGOs in the setting of developed countries and where the innovation brokerage is not recognized by the agricultural knowledge infrastructure (R&D institutions and extension services). Important outcome of this analysis was that innovation brokerage roles were crucial in agricultural innovation as it is beyond the capacity of R&D extension service. Hence, the Ministry of Agriculture Food Security and Cooperative and other relevant stakeholders should recognize the innovation brokerage roles and establish an institutional framework for its functioning within the agricultural knowledge infrastructure.