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Stephanostema Stenocarpum (Apocynaceae) Extract is a Potential Remedy for Bacterial Infections in Domestic Animals

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dc.creator Lyantagaye, Sylvester L.
dc.creator Magingo, Francis S.
dc.date 2016-09-21T13:40:13Z
dc.date 2016-09-21T13:40:13Z
dc.date 2010-12
dc.date.accessioned 2018-03-27T09:00:40Z
dc.date.available 2018-03-27T09:00:40Z
dc.identifier Lyantagaye, S.L. and Magingo, F.S., 2012. Stephanostema stenocarpum (Apocynaceae) extract is a potential remedy for bacterial infections in domestic animals. Journal of Medicinal Plants Research, 6(35), pp.4915-4921.
dc.identifier http://hdl.handle.net/20.500.11810/3973
dc.identifier 10.5897/JMPR10.883
dc.identifier.uri http://hdl.handle.net/20.500.11810/3973
dc.description Stephanostema is a monotypic genus whose sole specie Stephanostema stenocarpum is endemic to Tanzania. The liquid from boiled roots of this plant is being used by the local communities as a remedy of stomach-ache related ailments. The aim of the study was to evaluate antimicrobial activity of S. stenocarpum extracts against some common bacterial and fungal pathogens in domesticated animals and examine whether the crude extracts found active have cytotoxic effect or not. The standard growth inhibition technique was used for in vitro antimicrobial activity assay and the brine shrimp (BST) test was used to evaluate cytotoxicity of the extracts. Ethanolic extracts exhibited bacterial inhibitory growth activity against animal bacteria pathogens: Streptococcus agalactiae, Staphylococcus aureus, Salmonella gallinarum and Escherichia coli, but not active against the fungal strains tested. The study also showed that the extracts have no cytotoxicity effects. These results provide baseline information on the medicinal potential of S. stenocarpum as a new potential source of veterinary medicines.
dc.language en
dc.subject Stephanostema stenocarpum
dc.subject Phytotherapy
dc.subject Antibacterial
dc.subject Antifungal
dc.subject Cytotoxicity
dc.subject Veterinary
dc.title Stephanostema Stenocarpum (Apocynaceae) Extract is a Potential Remedy for Bacterial Infections in Domestic Animals
dc.type Journal Article, Peer Reviewed


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