There is no doubt that heritage resource loss in Tanzania is proceeding at an alarming rate. Natural and human agencies, adverse storage infrastructures and techniques, and lack of trained conservators and curators and of a proper protection program are the major threats that endanger the heritage resources of Tanzania. As our natural and cultural environments bring irreparable damage to the resources that document our human history, we need to preserve and protect them before they vanish. A preservation and protection program for Tanzania should include public education, the establishment of heritage preservation laws, more progress in the inventory and protection of in situ heritage resources, research into preservation and conservation methods, training of staff, and improvements in the curation of collected heritage resources and records. Preservation and protection of heritage resources are collaborative exercises. The scientific and world community need to support and engage in this proposed program both technically and financially, if the preservation and protection of heritage resources in Tanzania are to succeed.