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Antibiotic Containing Poly Lactic Acid/Hydroxyapatite Biocomposite Coatings for Dental Implant Applications

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dc.creator Karacan, Ipek
dc.creator Macha, Innocent J
dc.creator Choi, Gina
dc.creator Cazalbou, Sophie
dc.creator Ben-Nissan, Besim
dc.date 2019-02-15T19:25:28Z
dc.date 2019-02-15T19:25:28Z
dc.date 2017-11
dc.date.accessioned 2021-05-07T08:00:12Z
dc.date.available 2021-05-07T08:00:12Z
dc.identifier 1662-9795
dc.identifier http://hdl.handle.net/20.500.11810/5058
dc.identifier doi.org/10.4028/www.scientific.net/KEM.758.120
dc.identifier.uri http://hdl.handle.net/20.500.11810/5058
dc.description The biodegradable and biocompatible antibiotic containing thin film composites are very appropriate biomaterials as coating materials for dental implants because of their adjustable drug loading and release rates for the prevention of implant related infections. Coralline hydroxyapatite (HAp) was loaded with gentamicin antibiotics and combined with a biodegradable polylactic acid (PLA) to form thin film composites. PLA-HAp, PLA-Gentamicin (GM) and PLA-HAp-GM composites were produced, and their dissolution studies were carried out in phosphate buffered saline under SINK conditions. It was observed that the coatings could be efficiently applied to titanium dental implants and the drug release rates can be efficiently controlled.
dc.language en
dc.publisher Trans Tech Publications Inc
dc.subject Coating Dental Implants, Drug Release Studies, Hard Coral, Hydroxyapatite, PLA Thin Film Composites
dc.title Antibiotic Containing Poly Lactic Acid/Hydroxyapatite Biocomposite Coatings for Dental Implant Applications
dc.type Journal Article, Peer Reviewed


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