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A review of the newly identified impurity profiles in methamphetamine seizures

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dc.creator Onoka, Isaac
dc.creator Banyika, Andrew Toyi
dc.creator Banerjee, Protibha Nath
dc.creator Makangara, John J.
dc.creator Dujourdy, Laurence 2021-05-05T12:52:22Z 2021-05-05T12:52:22Z 2020 2021-05-06T13:10:16Z 2021-05-06T13:10:16Z
dc.identifier Onoka, I., Banyika, A. T., Banerjee, P. N., Makangara, J. J., & Dujourdy, L. (2020). A review of the newly identified impurities profiles in methamphetamine seizures. Forensic Science International: Synergy. 2, 194-205
dc.identifier DOI: 10.1016/j.fsisyn.2020.06.004
dc.description Full text article. Also available at
dc.description Forensic intelligence of synthetic illicit drugs suffers a problem of continuous introduction of new synthetic methods, modification of the existing routes of manufacture, and adulterations practiced by criminal networks. Impurity profiling has been indispensable in methamphetamine intelligence based on precursors, synthetic routes, and chemical modifications during trafficking. Law enforcement authorities maintain the credibility and integrity of intelligence information through constant monitoring of the chemical signatures in the illicit drug market. Changes in the synthetic pattern result in new impurity profiles that are important in keeping valuable intelligence information on clandestine laboratories, new synthetic routes, trafficking patterns, and geographical sources of illicit Methamphetamine. This review presents a critical analysis of the methamphetamine impurity profiles and more specifically, profiling based on impurity profiles from Leuckart, Reductive amination, Moscow, Emde, Nagai, Birch, Moscow route; a recent nitrostyrene route and stable isotope signatures. It also highlights the discrimination of ephedrine from pseudoephedrine sources and the emerging methamphetamine profiling based on stable isotopes.
dc.language en
dc.publisher Elsevier
dc.subject Methamphetamine
dc.subject Impurity profiles
dc.subject Stable isotopes
dc.subject Synthetic route
dc.subject Forensic intelligence
dc.subject Methamphetamine intelligence
dc.subject Illicit drugs
dc.subject Methamphetamine production
dc.subject Isotopes
dc.title A review of the newly identified impurity profiles in methamphetamine seizures
dc.type Article

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