Prevalence, etiology, antibiotic susceptibility and predictors of urinary tract infection among under fives with severe acute malnutrition admitted at referral hospitals, Tanzania

Luhaga, Rina Mbuke

dc.creator	Luhaga, Rina Mbuke
dc.date	2022-03-02T13:53:44Z
dc.date	2022-03-02T13:53:44Z
dc.date	2021
dc.date.accessioned	2022-10-20T14:03:24Z
dc.date.available	2022-10-20T14:03:24Z
dc.identifier	Luhaga, R. M. (2021). Prevalence, etiology, antibiotic susceptibility and predictors of urinary tract infection among under fives with severe acute malnutrition admitted at referral hospitals, Tanzania (Master's dissertation). The University of Dodoma, Dodoma.
dc.identifier	http://hdl.handle.net/20.500.12661/3405
dc.identifier.uri	http://hdl.handle.net/20.500.12661/3405
dc.description	Dissertation (MMED Pediatric and Child Health)
dc.description	The children with Severe Acute Malnutrition are at higher risk of getting severe infections compared to their counterparts due to state of immune deficiency. A cross-sectional analytical study was done at Dodoma and Iringa Regional Referral Hospitals and involved a total of 248 children aged 6 to 59 months. The structured questionnaires were used to collect social demographic, clinical and physical characteristics data. Urine samples taken were cultured according to standard operating procedures. The data were analyzed using SPSS version 26. Out of 248 participants; 148(59.7%) were males. The median age was 20.7(IQR: 14 – 30) months. The total of 50(20.16%) children had significant bacteriuria of gram-negative enteric bacteria. Escherichia coli 30/50(60%) and Klebsiella pneumoniae 15/50(30%) were predominant isolates. The susceptibility rate for E. coli was 29/30(96.67%), 30/30(100%), 30/30(100.00%), 26/30(86.67%), 5/30(16.67%), 19(63.33), 0(0.00%) for Ciprofloxacin, Meropenem, Amikacin, Amoxicillin/Clavulanic acid, Ceftazidime, Ceftriaxone and Gentamycin respectively. The presence of urine nitrite, urine sediments, increased frequency, painful urination, and female gender were predictors of positive urine culture (p <0.05). Gram-negative enteric bacteria resistant to Gentamycin and third- generation Cephalosporin constituted a common cause of significant bacteriuria in under-fives with Severe Acute Malnutrition.
dc.language	en
dc.publisher	The University of Dodoma
dc.subject	Urinary Tract Infection
dc.subject	UTI
dc.subject	Malnutrition
dc.subject	Severe Acute Malnutrition
dc.subject	Kwashiorkor
dc.subject	Marasmus
dc.subject	Dodoma
dc.title	Prevalence, etiology, antibiotic susceptibility and predictors of urinary tract infection among under fives with severe acute malnutrition admitted at referral hospitals, Tanzania
dc.type	Dissertation