Dissertation (MA Sociology)This study aimed at exploring the contribution of socio-cultural practices to the outbreak of Cholera. The study involved three villages of Kaseni, Galu, and Kamasi in Ilangala ward within Ukerewe District. Data were collected through social survey, in-depth interview, focus group discussion and documentary review. Both purposeful and simple random sampling procedures were used for sample selection. About 119 respondents were involved in this study. Statistical Package for Social Science (SPSS version 20) and Microsoft Excel were applied to analyze the data and then presented through tables, figures, plates, and texts. The research divulged that the objective of this study was to exploring the contribution of socio- cultural factors practices to the Outbreak of Cholera. The specific objectives of this study were to identify socio-cultural practices that contribute to the outbreak of Cholera. The second was to examine awareness of hygiene and sanitation and its contribution to Cholera outbreak, and the last one, is to identify the ways of preventing Cholera outbreak. The findings revealed that the main cause of the cholera outbreak in Ukerewe was undergoing defecation out of toilets, not washing hands after visiting latrine, drinking unboiled water, eating uncovered and cold food, poor hygiene, and sanitation including the absence of the pit latrines. Find also revealed ways of preventing cholera outbreak including thorough provision of education is highly encouraged, improving existing physical infrastructure, enforcement of laws on hygiene and sanitation to curb the situation and to end the cholera history in Ukerewe. Hence the study suggested that intersectoral collaborations among institutions, like Government Ministries, departments, and NGOs on preventing and controlling the outbreak of cholera are essential.