Porcine reproductive and respiratory syndrome virus entry into the porcine macrophage

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dc.creatorBreedam, W. V.
dc.creatorDelputte, P. L.
dc.creatorVan Gorp, H.
dc.creatorMisinzo, G.
dc.creatorVanderheijden, N.
dc.creatorDuan, X.
dc.creatorNauwynck, H. J.
dc.date2017-06-24T14:04:26Z
dc.date2017-06-24T14:04:26Z
dc.date2010
dc.date.accessioned2022-10-25T08:51:39Z
dc.date.available2022-10-25T08:51:39Z
dc.descriptionJournal of General Virology 2010, Vol. 91: 1659–1667
dc.descriptionPorcine reproductive and respiratory syndrome virus (PRRSV) emerged in the late 1980s and rapidly became one of the most significant viral pathogens in the swine industry. In vivo, the virus shows a very narrow cell tropism and targets specific subsets of porcine macrophages. The entry of PRRSV into its host cell is the first crucial step in infection and has been the focus of many fundamental studies. This review provides a comprehensive overview of the current knowledge on PRRSV entry into the porcine macrophage, covering virus binding, internalization and genome release, and integrates these findings into a general model of the entry process.
dc.formatapplication/pdf
dc.identifierhttps://www.suaire.sua.ac.tz/handle/123456789/1719
dc.identifier.urihttp://hdl.handle.net/123456789/91600
dc.languageen
dc.publisherJournal of General Virology
dc.subjectSyndrome virus
dc.subjectPorcine macrophage
dc.subjectPorcine reproductive
dc.subjectPRRSV
dc.subjectArteriviridae
dc.subjectNidovirales
dc.titlePorcine reproductive and respiratory syndrome virus entry into the porcine macrophage
dc.typeArticle

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