Treponema infection associated with genital ulceration in wild baboons

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dc.creatorKnauf, S
dc.creatorBatamuzi, E. K
dc.creatorMlengeya, T
dc.creatorKilewo, M
dc.creatorLejora, I. A. V
dc.creatorNordhoff, M
dc.creatorEhlers, B
dc.creatorHarper, K. N
dc.creatorFyumagwa, R
dc.creatorHoare, R
dc.creatorFailing, K
dc.creatorWehrend, A
dc.creatorKaup, F. J
dc.creatorLeendertz, F. H
dc.creatorMätz-Rensing, K
dc.date2022-05-17T10:03:00Z
dc.date2022-05-17T10:03:00Z
dc.date2012
dc.date.accessioned2022-10-25T08:50:41Z
dc.date.available2022-10-25T08:50:41Z
dc.descriptionThe authors describe genital alterations and detailed histologic findings in baboons naturally infected with Treponema pallidum. The disease causes moderate to severe genital ulcerations in a population of olive baboons (Papio hamadryas anubis) at Lake Manyara National Park in Tanzania. In a field survey in 2007, 63 individuals of all age classes, both sexes, and different grades of infection were chemically immobilized and sampled. Histology and molecular biological tests were used to detect and identify the organism responsible: a strain similar to T pallidum ssp pertenue, the cause of yaws in humans. Although treponemal infections are not a new phenomenon in nonhuman primates, the infection described here appears to be strictly associated with the anogenital region and results in tissue alterations matching those found in human syphilis infections (caused by T pallidum ssp pallidum), despite the causative pathogen’s greater genetic similarity to human yaws-causing strains.
dc.formatapplication/pdf
dc.identifier292-303
dc.identifierhttps://www.suaire.sua.ac.tz/handle/123456789/4143
dc.identifier.urihttp://hdl.handle.net/123456789/90523
dc.languageen
dc.publisherThe American College of Veterinary Pathologists
dc.subjectTreponema pallidum
dc.subjectGenital
dc.subjectHistology
dc.subjectImmunohistochemistry
dc.subjectNonhuman primate
dc.subjectOlive baboon (Papio hamadryas anubis)
dc.subjectSexually transmitted disease
dc.subjectSyphilis
dc.titleTreponema infection associated with genital ulceration in wild baboons
dc.typeArticle

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