"Gairovirus,anovelarena virusof the widespread Mastomys natalensis: genetically divergent,but ecologically similar to Lassa and Morogoro viruses

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dc.creatorGryseels, Sophie
dc.creatorRieger, Toni
dc.creatorOestereich, Lisa
dc.creatorCuypers, Bart
dc.creatorBorremans, Benny
dc.creatorMakundi, Rhodes
dc.creatorLeirs, Herwig
dc.creatorGünther, Stephan
dc.creatorGoüy de Bellocq, Joëlle
dc.date2016-12-06T06:27:37Z
dc.date2016-12-06T06:27:37Z
dc.date2015
dc.date.accessioned2022-10-25T08:52:26Z
dc.date.available2022-10-25T08:52:26Z
dc.descriptionDespite itsnearpan-Africanrange,theNatalmultimammatemouse, Mastomysnatalensis, carriesthe human pathogenLassavirusonlyinWestAfrica,whiletheseeminglynon-pathogenicarenaviruses Mopeia, Morogoro,andLunahavebeendetectedinthissemi-commensalrodentinMozambique/ Zimbabwe,TanzaniaandZambia,respectively.Here,wedescribeanovelarenavirusin M. natalensis from Gairo districtofcentralTanzania,forwhichweproposethename “Gairo virus”. Surprisingly,thevirusis not closelyrelatedwithMorogorovirusthatinfects M. natalensis only 90kmsouthofGairo,butclusters phylogeneticallywithMobala-likevirusesthatinfectnon-M. natalensis host speciesinCentralAfrican RepublicandEthiopia.Despitetheevolutionarydistance,Gairovirussharesbasicecologicalfeatures with theother M. natalensis-borne virusesLassaandMorogoro.Ourdatashowthat M. natalensis, carrying distantlyrelatedviruseseveninthesamegeographicalarea,isapotentreservoirhostfora varietyofarenaviruses.
dc.formatapplication/pdf
dc.identifierhttps://www.suaire.sua.ac.tz/handle/123456789/1085
dc.identifier.urihttp://hdl.handle.net/123456789/92551
dc.languageen
dc.publisherElsevierInc
dc.subjectArenavirus
dc.subjectMastomys natalensis
dc.subjectVirology
dc.subjectPhylogeny
dc.subjectEcology
dc.subjectZoonotic infections
dc.subjectHemorrhagic fevers
dc.subjectTanzania
dc.title"Gairovirus,anovelarena virusof the widespread Mastomys natalensis: genetically divergent,but ecologically similar to Lassa and Morogoro viruses
dc.typeArticle

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