Household Epidemics: Modelling Effects of Early Stage Vaccination

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dc.creatorShaban, Nyimvua
dc.creatorAndersson, Mikael
dc.creatorSvensson, Åke
dc.creatorBritton, Tom
dc.date2016-09-21T17:24:23Z
dc.date2016-09-21T17:24:23Z
dc.date2009
dc.date.accessioned2018-03-27T08:58:15Z
dc.date.available2018-03-27T08:58:15Z
dc.descriptionA Markovian susceptible - infectious - removed (SIR) epidemic model is considered in a community partitioned into households. A vaccination strategy, which is implemented during the early stages of the disease following the detection of infected individuals is proposed. In this strategy, the detection occurs while an individual is infectious and other susceptible household members are vaccinated without further delay. Expressions are derived for the influence on the reproduction numbers of this vaccination strategy for equal and unequal household sizes. We fit previously estimated parameters from influenza and use household distributions for Sweden and Tanzania census data. The results show that the reproduction number is much higher in Tanzania (6 compared with 2) due to larger households, and that infected individuals have to be detected (and household members vaccinated) after on average 5 days in Sweden and after 3.3 days in Tanzania, a much smaller difference.
dc.identifierShaban, N., Andersson, M., Svensson, Å. and Britton, T., 2009. Household epidemics: modelling effects of early stage vaccination. Biometrical Journal, 51(3), pp.408-419.
dc.identifierhttp://hdl.handle.net/20.500.11810/4176
dc.identifier10.1002/bimj.200800172
dc.identifier.urihttp://hdl.handle.net/20.500.11810/4176
dc.languageen
dc.publisherWiley
dc.subjectDelay time
dc.subjectEpidemic model
dc.subjectHousehold
dc.subjectReproduction number
dc.subjectVaccination strategy
dc.titleHousehold Epidemics: Modelling Effects of Early Stage Vaccination
dc.typeJournal Article, Peer Reviewed

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