Occurrence of Foot-and-Mouth Disease Virus Serotypes in Uganda and Tanzania (2003 to 2015): A Review and Implications for Prospective Regional Disease Control

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dc.creatorKerfua, Susan
dc.creatorDhikusooka, Moses
dc.creatorMulondo, Alice
dc.creatorBugeza, James
dc.creatorKabi, Fredrick
dc.creatorShirima, Gabriel
dc.creatorKusiluka, Lughano
dc.creatorAyebazibwe, Chrisostome
dc.creatorCleaveland, Sarah
dc.creatorHaydon, Daniel
dc.date2020-06-12T08:29:13Z
dc.date2020-06-12T08:29:13Z
dc.date2020-05-15
dc.date.accessioned2022-10-25T09:20:48Z
dc.date.available2022-10-25T09:20:48Z
dc.descriptionThis research article published by the Journal of Agricultural Science, 2020
dc.descriptionEndemic foot-and-mouth disease (FMD) presents a global economic challenge to the livestock industry. The progressive control pathway for FMD (PCP-FMD) specifies successive steps through which a country/region can reduce FMD virus circulation and impact. These steps are reliant on understanding and obtaining knowledge on FMD epidemiology, to inform development of appropriate disease interventions like vaccination and quarantine programs. Currently, Uganda and Tanzania are in the early stages of the PCP-FMD. This review was undertaken to determine FMDV serotype distribution in Uganda and Tanzania between 2003 and 2015. The paper also presents the vaccine strains used in both countries for the same period viz avis the circulating topotypes. The review highlights four (O, A, SAT 1 and SAT 2) and five (O, A, SAT 1, SAT 2 and SAT 3) serotypes that occurred in Uganda and Tanzania respectively in the thirteen year period. Observations revealed that reported circulating serotypes O and A in the two countries belonged to similar topotypes, East African 2 (EA-2) and AFRICA respectively. The SAT 1 viruses in Tanzania belonged to topotype I and differed from the Ugandan SAT 1s that belonged to topotype IV. Similarly, the SAT 2s in both countries belonged to different topotypes: IV in Tanzania and I in Uganda. This review additionally, underscores the spatial distribution of FMDV serotypes in Uganda and Tanzania and highlights regions in both countries that had high serotype diversity. The paper recommends definitive disease diagnoses, molecular serotype characterisation and matched vaccination deployment for improved disease control.
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dc.identifierhttps://doi.org/10.5539/jas.v12n6p119
dc.identifierhttps://dspace.nm-aist.ac.tz/handle/20.500.12479/791
dc.identifier.urihttp://hdl.handle.net/123456789/95256
dc.languageen
dc.publisherJournal of Agricultural Science
dc.subjectFoot-and-mouth disease
dc.titleOccurrence of Foot-and-Mouth Disease Virus Serotypes in Uganda and Tanzania (2003 to 2015): A Review and Implications for Prospective Regional Disease Control
dc.typeArticle

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