First Report of the Co-occurrence of Cylindrospermopsin, Nodularin and Microcystins in the Freshwaters of Lake Victoria, Tanzania

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dc.creatorMchau, Geofrey
dc.creatorMachunda, Revocatus
dc.creatorKimanya, Martin
dc.creatorMakule, Edna
dc.creatorGong, Yun
dc.creatorMpolya, Emmanuel
dc.creatorMeneely, Julie
dc.creatorElliott, Christopher
dc.creatorGreer, Brett
dc.date2020-08-11T07:28:10Z
dc.date2020-08-11T07:28:10Z
dc.date2020-07-26
dc.date.accessioned2022-10-25T09:24:51Z
dc.date.available2022-10-25T09:24:51Z
dc.descriptionThis research article published by Springer Nature Switzerland AG., 2020
dc.descriptionThere is a global concern regarding the increase of cyanotoxins in freshwater and their potential effects on human health. The existence of multiple toxins in freshwater can result in an increased risk of their bioaccumulation in humans from their ingestion through contaminated drinking water or recreational activities. This study, the first of its kind, was conducted to determine the occurrence of thirteen cyanotoxins namely; microcystins (-LA, -LF, -LR, -LY, -LW, -RR, -YR, -WR, dm MC-RR and dm MC-LR), anatoxin-a, nodularin and cylindrospermopsin in the freshwaters of Lake Victoria in Tanzania. A total of 23 sites were selected for water sampling. Samples were randomly collected from lakeshores (n = 54), wells (n = 66) and piped water (n = 18) in two phases, February (dry season) and December (rainy season) 2018. Samples (n = 138) were analysed using liquid chromatography mass spectrometry (UPLC-MS/MS). Cylindrospermopsin was the most abundant cyanotoxin detected in the lakeshores, with eight of the nine collection sites (89%) reporting cylindrospermopsin in phase I, compared to three out of nine (33%) in phase II. Microcystin congeners -RR, -LR and -YR were detected in phase I, with microcystins -RR and -LR detected in phase II. MC concentrations ranged from 0.003 to 0.007 μg/L for MC-RR, 0.01–0.013 μg/L for MC-LR and 0.004 to 0.01 μg/L for cylindrospermopsin, with nodularin reported once at a concentration of 0.01 μg/L. No cyanotoxins were detected in wells or in treated pipe water samples. The existence of multiple toxins in different collection sites may lead to synergistic effects and increase the toxicological risk to humans. This is the first study to report the presence of cylindrospermopsin and nodularin in the freshwaters of Lake Victoria.
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dc.identifierhttps://doi.org/10.1007/s12403-020-00372-7
dc.identifierhttps://dspace.nm-aist.ac.tz/handle/20.500.12479/860
dc.identifier.urihttp://hdl.handle.net/123456789/95828
dc.languageen
dc.publisherSpringer Nature Switzerland AG.
dc.subjectCylindrospermopsin
dc.subjectLake Victoria
dc.subjectNodularin
dc.subjectMicrocystin
dc.titleFirst Report of the Co-occurrence of Cylindrospermopsin, Nodularin and Microcystins in the Freshwaters of Lake Victoria, Tanzania
dc.typeArticle

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