Immunohistochemical detection of Mycoplasma mucoid mucoid small colony type in lungs of slaughtered cattle at Morogoro slaughterhouse, Tanzania

dc.creatorMalago, J. J.
dc.creatorMlay, J. D.
dc.date2018-06-17T10:19:35Z
dc.date2018-06-17T10:19:35Z
dc.date2015
dc.date.accessioned2022-10-25T08:53:46Z
dc.date.available2022-10-25T08:53:46Z
dc.descriptionTanzania Veterinary Journal
dc.descriptionDiagnosis of contagious bovine pleuropneumonia (CBPP) in carrier animals remains to be a challenge in developing countries partly because of lack of diagnostic tools that can detect asymptomatic animals. As a result many apparently healthy animals pose a potential impending epidemic in periods of stress. We examined condemned lungs with CBPP-like lesions from apparently healthy slaughtered animals to confirm presence of the disease in these animals. A total of 13 lungs collected at abattoir were examined immunohistochemically using 3H12 and 6E3 monoclonal antibodies against Mycoplasma mycoides mycoides (MmmSC), the causative agent of CBPP. Both 3H12 and 6E3 antibodies detected the MmmSC antigens in all the 13 lungs in bronchial, bronchiolar and alveolar epithelia, bronchial glands, bronchial cartilage, and in alveoli. We conclude that CBPP is still present in various places of Tanzania, posing a threat to livestock production and that immunohistochemistry can be an efficient diagnostic method to confirm presence of the disease in asymptomatic healthy animals passed for slaughter.
dc.formatapplication/pdf
dc.identifierhttps://www.suaire.sua.ac.tz/handle/123456789/2369
dc.identifier.urihttp://hdl.handle.net/123456789/94126
dc.languageen
dc.publisherTanzania Veterinary Journal
dc.subjectCBPP
dc.subjectCattle
dc.subjectMonoclonal antibody
dc.subjectLung parenchyma
dc.subjectMmmSC antigens
dc.subjectImmunohistochemistry
dc.titleImmunohistochemical detection of Mycoplasma mucoid mucoid small colony type in lungs of slaughtered cattle at Morogoro slaughterhouse, Tanzania
dc.typeArticle

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