Seroprevalence of circulating taeniid antigens in pigs and associated risk factors in Kongwa district, Tanzania

Simple item page
dc.creatorMaganira, Justine Daudi
dc.creatorMwang'onde, Beda John
dc.creatorKidima, Winifrida
dc.creatorMwita, Chacha John
dc.creatorHöglund, Johan
dc.date2021-08-06T05:19:39Z
dc.date2021-08-06T05:19:39Z
dc.date2019
dc.date.accessioned2022-10-25T08:51:59Z
dc.date.available2022-10-25T08:51:59Z
dc.descriptionJournal article
dc.descriptionThe aim of this study was to investigate exposure to porcine cysticercosis (PC) and associated risk factors in the Kongwa District, eastern-central Tanzania. For the first time a cross-sectional investigation of the seroprevalence in pigs using a commercial genus specific cysticercosis enzyme linked immunosorbent assay (apDia Ag-ELISA) was undertaken in eastern-central Tanzania. Moreover, the identity of suspected T. solium cysts from pigs in the study area were confirmed by sequencing parasites’ mitochondrial cox1 gene. Structured questionnaires and direct observations were used to investigate risk factors associated with parasite transmission. A total of 102 pig-keeping households were surveyed during the dry season between July and August 2017 and 126 households in the rainy season between March and April 2018. Of the 447 examined pigs, 77 (17%, 95% C.I. 14%e20%) tested positive in the ELISA. Seroprevalence was higher in pigs examined during the rainy (21%, 95% C.I. 16%e26%) than dry (12%, 95% C.I. 7%e17%) season (p ¼ 0.019). Eight cyst-positive-pigs were confirmed to be infected with T. solium by sequencing. Risk factors associated with PC seropositivity included origin of piglets or pigs (OR ¼ 0.27, 95% C.I. 0.13 e0.42, p ¼ 0.001), socioeconomic factors and pig production system (OR ¼ 0.22, 95% C.I. 0.07e0.37, p ¼ 0.005) and sanitation and hygiene practices (OR ¼ 0.19, 95% C.I. 0.04e0.34, p ¼ 0.014). This study has recorded a high Taenia spp. seroprevalence in pigs in Kongwa suggesting the presence of people in the community carrying the adult parasite, Taenia solium. Our findings also suggest risk of infection by T. solium to people in urban centres and cities consuming pigs from rural areas in Kongwa. The high seroprevalence in Kongwa calls for further studies on taeniasis and cysticercosis in the human population in order to determine suitable control strategies.
dc.formatapplication/pdf
dc.identifierhttps://www.suaire.sua.ac.tz/handle/123456789/3834
dc.identifier.urihttp://hdl.handle.net/123456789/92023
dc.languageen
dc.publisherElsevier
dc.subjectTaenia solium
dc.subjectSeroprevalence
dc.subjectPorcine cysticercosis
dc.subjectAntigen
dc.subjectKongwa
dc.subjectTanzania
dc.titleSeroprevalence of circulating taeniid antigens in pigs and associated risk factors in Kongwa district, Tanzania
dc.typeArticle

Files

Collections

Sokoine University