African 2, a clonal complex of mycobacterium bovis epidemiologically important in East Africa

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dc.creatorStefan, Berg, M
dc.creatorBorna, Müller
dc.creatorElena, Hailu
dc.creatorBenon, Asiimwe
dc.creatorKristin, Kremer
dc.creatorJames, Dale M
dc.creatorBeatrice, Boniotti
dc.creatorSabrina, Rodriguez
dc.creatorMarkus, Hilty
dc.creatorLeen, Rigouts
dc.creatorRebuma, Firdessa
dc.creatorAdelina, Machado
dc.creatorCustodia, Mucavele
dc.creatorBongo, Nare R. N
dc.creatorBruchfeld, Judith
dc.creatorBoschiroli, Laura
dc.creatorMüller, Annélle
dc.creatorSahraoui, Naima
dc.creatorPacciarini, Maria
dc.creatorCadmus, Smeoni
dc.creatorJoloba, Moses
dc.creatorJoloba, Moses
dc.creatorSoolingen, Dick v
dc.creatorMichel, Anita L.
dc.creatorDjønne, Berit
dc.creatorAranaz, Alicia
dc.creatorZinsstag, Jakob
dc.creatorPortaels, Françoise
dc.creatorKazwala, Rudovick
dc.creatorKällenius, Gunilla
dc.creatorHewinson, Glyn
dc.creatorAseffa, Abraham
dc.creatorGordon, Stephen V.
dc.creatorSmith, Noel H.
dc.creatorGarcia-Pelayo, M. Carmen
dc.date2022-05-17T09:31:42Z
dc.date2022-05-17T09:31:42Z
dc.date2011
dc.date.accessioned2022-10-25T08:51:42Z
dc.date.available2022-10-25T08:51:42Z
dc.descriptionWe have identified a clonal complex of Mycobacterium bovis isolated at high frequency from cattle in Uganda, Burundi, Tanzania, and Ethiopia. We have named this related group of M. bovis strains the African 2 (Af2) clonal complex of M. bovis. Af2 strains are defined by a specific chromosomal deletion (RDAf2) and can be identified by the absence of spacers 3 to 7 in their spoligotype patterns. Deletion analysis of M. bovis isolates from Algeria, Mali, Chad, Nigeria, Cameroon, South Africa, and Mozambique did not identify any strains of the Af2 clonal complex, suggesting that this clonal complex of M. bovis is localized in East Africa. The specific spoligotype pattern of the Af2 clonal complex was rarely identified among isolates from outside Africa, and the few isolates that were found and tested were intact at the RDAf2 locus. We conclude that the Af2 clonal complex is localized to cattle in East Africa. We found that …
dc.formatapplication/pdf
dc.identifier0021-9193
dc.identifierhttps://www.suaire.sua.ac.tz/handle/123456789/4140
dc.identifier.urihttp://hdl.handle.net/123456789/91666
dc.languageen
dc.publisherAmerican Society for Microbiology
dc.subjectMycobacterium bovis
dc.subjectEast Africa
dc.titleAfrican 2, a clonal complex of mycobacterium bovis epidemiologically important in East Africa
dc.typeArticle

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