Using giant African pouched rats to detect tuberculosis in human sputum samples: 2010 findings

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dc.creatorMahoney, A.M
dc.creatorWeetjens, B.J
dc.creatorCox, C
dc.creatorBeyene, N
dc.creatorMgode, G
dc.creatorJubitana, M
dc.creatorKuiper, D
dc.creatorKazwala, R
dc.creatorMfinanga, G.S
dc.creatorDurgin, A
dc.creatorPoling, A
dc.date2017-04-04T12:17:17Z
dc.date2017-04-04T12:17:17Z
dc.date2011-07-17
dc.date.accessioned2022-10-25T08:50:13Z
dc.date.available2022-10-25T08:50:13Z
dc.descriptionPan African Medical Journal 2011, Vol 9:28
dc.descriptionGiant African pouched rats previously have detected tuberculosis (TB) in human sputum samples in which the presence of TB was not initially detected by smear microscopy. Operant conditioning principles were used to train these rats to indicate TB-positive samples. In 2010, rats trained in this way evaluated 26,665 sputum samples from 12,329 patients. Microscopy performed at DOTS centers found 1,671 (13.6%) of these patients to be TB-positive. Detection rats identified 716 additional TB-positive patients, a 42.8% increase in new-case detection. These previously unreported data, which extend to over 20,000 the number of patients evaluated by pouched rats in simulated second-line screening, suggest that the rats can be highly valuable in that capacity.
dc.formatapplication/pdf
dc.identifier1937- 8688
dc.identifierhttps://www.suaire.sua.ac.tz/handle/123456789/1378
dc.identifier.urihttp://hdl.handle.net/123456789/89934
dc.languageen
dc.subjectGiant African pouched
dc.subjectTuberculosis
dc.subjectHuman sputum
dc.subjectTB
dc.titleUsing giant African pouched rats to detect tuberculosis in human sputum samples: 2010 findings
dc.typeArticle

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