Antibiotic Containing Poly Lactic Acid/Hydroxyapatite Biocomposite Coatings for Dental Implant Applications

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dc.creatorKaracan, Ipek
dc.creatorMacha, Innocent J
dc.creatorChoi, Gina
dc.creatorCazalbou, Sophie
dc.creatorBen-Nissan, Besim
dc.date2019-02-15T19:25:28Z
dc.date2019-02-15T19:25:28Z
dc.date2017-11
dc.date.accessioned2021-05-07T08:00:12Z
dc.date.available2021-05-07T08:00:12Z
dc.descriptionThe biodegradable and biocompatible antibiotic containing thin film composites are very appropriate biomaterials as coating materials for dental implants because of their adjustable drug loading and release rates for the prevention of implant related infections. Coralline hydroxyapatite (HAp) was loaded with gentamicin antibiotics and combined with a biodegradable polylactic acid (PLA) to form thin film composites. PLA-HAp, PLA-Gentamicin (GM) and PLA-HAp-GM composites were produced, and their dissolution studies were carried out in phosphate buffered saline under SINK conditions. It was observed that the coatings could be efficiently applied to titanium dental implants and the drug release rates can be efficiently controlled.
dc.identifier1662-9795
dc.identifierhttp://hdl.handle.net/20.500.11810/5058
dc.identifierdoi.org/10.4028/www.scientific.net/KEM.758.120
dc.identifier.urihttp://hdl.handle.net/20.500.11810/5058
dc.languageen
dc.publisherTrans Tech Publications Inc
dc.subjectCoating Dental Implants, Drug Release Studies, Hard Coral, Hydroxyapatite, PLA Thin Film Composites
dc.titleAntibiotic Containing Poly Lactic Acid/Hydroxyapatite Biocomposite Coatings for Dental Implant Applications
dc.typeJournal Article, Peer Reviewed

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Department of Mechanical and Industrial Engineering