Recombination, selection and clock-like evolution of Rice yellow mottle virus

Simple item page
dc.creatorGalzi, Agnès P.
dc.creatorMpunami, Anatolia
dc.creatorSangu, Emmanuel
dc.creatorRakotomalala, Mbolarinosy
dc.creatorTraore, Oumar
dc.creatorSereme, Drissa
dc.creatorFatogoma, Sorho
dc.creatorSere, Y.
dc.creatorKanyeka, Zakaria L.
dc.creatorKonaté, Gnissa
dc.creatorFargette, Denis
dc.date2016-07-08T12:14:29Z
dc.date2016-07-08T12:14:29Z
dc.date2009-09
dc.date.accessioned2018-03-27T08:55:38Z
dc.date.available2018-03-27T08:55:38Z
dc.descriptionThe clock-like diversification of Rice yellow mottle virus (RYMV), a widespread RNA plant virus that infects rice in Africa, was tested following a three-step approach with (i) an exhaustive search of recombinants, (ii) a comprehensive assessment of the selective constraints over lineages, and (iii) a stepwise series of tests of the molecular clock hypothesis. The first evidence of recombination in RYMV was found in East Africa, in the region most favorable to co-infection. RYMV evolved under a pronounced purifying selection, but the selection pressure did vary among lineages. There was no phylogenetic evidence of transient deleterious mutations. ORF2b, which codes for the polymerase and is the most constrained ORF, tends to diversify clock-like. With the other ORFs and the full genome, the departure from the strict clock model was limited. This likely reflects the dominant conservative selection pressure and the clock-like fixation of synonymous mutations.
dc.identifierPinel-Galzi, A., Mpunami, A., Sangu, E., Rakotomalala, M., Traoré, O., Sérémé, D., Sorho, F., Séré, Y., Kanyeka, Z., Konaté, G. and Fargette, D., 2009. Recombination, selection and clock-like evolution of Rice yellow mottle virus. Virology, 394(1), pp.164-172.
dc.identifierhttp://hdl.handle.net/20.500.11810/2889
dc.identifier10.1016/j.virol.2009.08.008 · Source: PubMed
dc.identifier.urihttp://hdl.handle.net/20.500.11810/2889
dc.languageen
dc.publisherElsevier
dc.subjectMolecular clock
dc.subjectRecombination
dc.subjectSelection pressure
dc.subjectPhylogeography
dc.titleRecombination, selection and clock-like evolution of Rice yellow mottle virus
dc.typeJournal Article, Peer Reviewed

Files

Collections

Department of Botany