Using giant african pouched rats to detect human tuberculosis: A review

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dc.creatorPoling, A.
dc.creatorMahoney, A.
dc.creatorBeyene, N.
dc.creatorMgode, G.
dc.creatorWeetjens, B.
dc.creatorCox, C.
dc.creatorDurgin, A.
dc.date.accessioned2020-06-19T11:33:53Z
dc.date.accessioned2025-08-05T07:38:20Z
dc.date.available2020-06-19T11:33:53Z
dc.date.created2020-06-19T11:33:53Z
dc.date.issued2015-08-31
dc.description.abstractDespite its characteristically low sensitivity, sputum smear microscopy remains the standard for diagnosing tuberculosis (TB) in resource-poor countries. In an attempt to develop an alternative or adjunct to microscopy, researchers have recently examined the ability of pouched rats to detect TB-positive human sputum samples and the microbiological variables that affect their detection. Ten published studies, reviewed herein, suggest that the rats are able to detect the specific odor of Mycobacterium tuberculosis , which causes TB, and can substantially increase new-case detections when used for second-line TB screening following microscopy. Further research is needed to ascertain the rats' ability to detect TB in children and in HIV-positive patients, to detect TB when used for first-line screening, and to be useful in broad-scale applications where cost- effectiveness is a major consideration.
dc.identifier1937-8688
dc.identifierhttps://www.suaire.sua.ac.tz/handle/123456789/3093
dc.identifier.urihttp://repository.costech.or.tz/handle/20.500.14732/99142
dc.languageen
dc.publisherPan African Medical Journal
dc.subjectPouched rats
dc.subjectHuman tuberculosis
dc.subjectRats training
dc.subjectA review
dc.titleUsing giant african pouched rats to detect human tuberculosis: A review
dc.typeArticle

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