Seroprevalence and associated risk factors of chikungunya, dengue, and zika in eight districts in Tanzania

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dc.creatorMwanyika, Gaspary O.
dc.creatorSindato, Calvin
dc.creatorRugarabamu, Sima
dc.creatorRumisha, Susan F.
dc.creatorKarimuribo, Esron D.
dc.creatorMisinzo, Gerald
dc.creatorRweyemamu, Mark M.
dc.creatorHamid, Muzamil M. Abdel
dc.creatorHaider, Najmul
dc.creatorVairo, Francesco
dc.creatorKock, Richard
dc.creatorMboera, Leonard E.G.
dc.date2022-09-06T09:54:23Z
dc.date2022-09-06T09:54:23Z
dc.date2021
dc.date.accessioned2022-10-25T08:52:55Z
dc.date.available2022-10-25T08:52:55Z
dc.descriptionInternational Journal of Infectious Diseases 111 (2021) pp. 271–280
dc.descriptionBackground: This study was conducted to determine the seroprevalence and risk factors of chikungunya (CHIKV), dengue (DENV), and Zika (ZIKV) viruses in Tanzania. Methods: The study covered the districts of Buhigwe, Kalambo, Kilindi, Kinondoni, Kondoa, Kyela, Mvomero, and Ukerewe in Tanzania. Blood samples were collected from individuals recruited from house- holds and healthcare facilities. An ELISA was used to screen for immunoglobulin G antibodies against CHIKV, DENV, and ZIKV. Results: A total of 1818 participants (median age 34 years) were recruited. The overall CHIKV, DENV, and ZIKV seroprevalence rates were 28.0%, 16.1%, and 6.8%, respectively. CHIKV prevalence was highest in Buhigwe (46.8%), DENV in Kinondoni (43.8%), and ZIKV in Ukerewe (10.6%) and Mvomero (10.6%). Increas- ing age and frequent mosquito bites were significantly associated with CHIKV and DENV seropositivity ( P < 0.05). Having piped water or the presence of stagnant water around the home ( P < 0.01) were as- sociated with higher odds of DENV seropositivity. Fever was significantly associated with increased odds of CHIKV seropositivity ( P < 0.001). Visiting mines had higher odds of ZIKV seropositivity ( P < 0.05). Conclusions: These findings indicate that DENV, CHIKV, and ZIKV are circulating in diverse ecological zones of Tanzania. There is a need to strengthen the control of mosquito-borne viral diseases in Tanzania.
dc.formatapplication/pdf
dc.identifierhttp://www.suaire.sua.ac.tz/handle/123456789/4523
dc.identifier.urihttp://hdl.handle.net/123456789/93152
dc.languageen
dc.publisherElsevier Ltd
dc.subjectChikungunya
dc.subjectDengue Zika
dc.subjectSeroprevalence
dc.subjectRisk factors
dc.subjectTanzania
dc.titleSeroprevalence and associated risk factors of chikungunya, dengue, and zika in eight districts in Tanzania
dc.typeArticle

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