A Dissertation Submitted in Partial Fulfillment of the Requirements for Degree of Master in Procurement and Supply Chain Management (MSc. PSCM) of Mzumbe University.The main objective of this study was to assess the internal factors that affect the effective procurement processes for goods in Tanzanian Government Agencies. To achieve this main objective, the study used four specific objectives which are to examine the policy which govern procurement process for goods in Government Agencies in Tanzania, to examine the relationship between culture of employees and procurement process for goods in Government Agencies in Tanzania, to examine electronic infrastructure applied in the procurement processes of goods in Government Agencies in Tanzania and to determine the employees perception in the procurement processes of goods in Government Agencies in Tanzania. The case study design was used, whereby the Governments Chemist Laboratory Authority was chosen; and a total of 55 respondents was selected using purposive sampling technique. To get data, the study used the interviews, questionnaires and documents reviews and the Analysis was done using SPSS. The findings show that the internal factors affecting procurement processes are procurement policy, ICT infrastructures, and Employees cultures and employees perceptions. The findings show that the Procurement Policy, the ICT Infrastructures, and the cultures of employees affect positively the Procurement processes; but the Perceptions of employees were found to have negatively affected the procurement processes. The study recommends that strict measures be taken in case an employee regardless of the position is involved in corruption. The Anti corruption institution (PCCB) should also be alerted for any case of corruption so as the alleged be taken to court. It is also recommended that strict measures be always taken to anyone who has embezzled the funds. In addition, every person involved in funds embezzlement has to be taken to court to limit further occurrence of such unlawful acts. It is also recommended that training on code of conduct be organized several times, and the consequences associated with failure to observe laws and ethics during the procurement processes.