The aim of this paper is to measure the efficiency of listed manufacturing companies in Tanzania, the study covers the year 2010 to 2014. The study employed a non-parametric approach, known as Data Envelopment Analysis (DEA) to measure efficiency under input oriented with constant returns to scale (CRS) and variable returns to scale assumptions (VRS). The study also employs Pearson correlation to test positive correlation between inputs and outputs variables. Data was extracted from respective annual financial reports of the manufacturing firms listed at Dar es Salaam stock exchange (DSE) before the year 2010. Three critical inputs variables (raw materials, staff expenses as well as plant and machinery) and two output variables (net sales and earnings after tax) were employed to measure relative efficiency of 6 listed manufacturing. Findings revealed that Tanzania Cigarette Company (TCC) was …