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Antimicrobial resistance in human and animal pathogens in Zambia, Democratic Republic of Congo, Mozambique and Tanzania

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dc.creator Mshana, Stephen E
dc.creator Matee, Mecky
dc.creator Rweyemamu, Mark
dc.date 2022-06-08T10:10:00Z
dc.date 2022-06-08T10:10:00Z
dc.date 2013-12
dc.date.accessioned 2022-10-25T08:50:55Z
dc.date.available 2022-10-25T08:50:55Z
dc.identifier https://www.suaire.sua.ac.tz/handle/123456789/4226
dc.identifier.uri http://hdl.handle.net/123456789/90804
dc.description A review of the published and unpublished literature on bacterial resistance in human and animals was performed. Sixty-eight articles/reports from the Democratic Republic of Congo (DRC), Mozambique, Tanzania and Zambia were reviewed. The majority of these articles were from Tanzania. There is an increasing trend in the incidence of antibiotic resistance; of major concern is the increase in multidrug- resistant Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Vibrio cholera, non-typhoid Salmonella and other pathogens responsible for nosocomial infections. The increase in methicillin- resistant Staphylococcus aureus and extended-spectrum beta-lactamase (ESBL) producers in the countries under review confirms the spread of these clones worldwide. Clinical microbiology services in these countries need to be strengthened in order to allow a coordinated surveillance for antimicrobial resistance and provide data for local treatment guidelines and for national policies to control antimicrobial resistance. While the present study does not provide conclusive evidence to associate the increasing trend in antibiotic resistance in humans with the use of antibiotics in animals, either as feed additives or veterinary prescription, we strongly recommend a one-health approach of systematic surveillance across the public and animal health sectors, as well as the adherence to the FAO (Food and Agriculture Organization)-OIE (World Organization of animal Health) –WHO(World Health Organization) recommendations for non-human antimicrobial usage.
dc.format application/pdf
dc.language en
dc.publisher Annals of clinical microbiology and Antimicrobials
dc.subject Antimicrobial resitance
dc.subject Human
dc.subject Pathogens Zambia
dc.title Antimicrobial resistance in human and animal pathogens in Zambia, Democratic Republic of Congo, Mozambique and Tanzania
dc.title an urgent need of a sustainable surveillance system
dc.type Article


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