Journal of Continuing Education and Extension, 2014; 5(2): 706-721This study was carried out in Masasi and Nachingwea districts in Tanzania to provide empirical evidence of existing local knowledge (LK) related to agrobiodiversity surrounding the local communities and how that knowledge contributes to adaptation to climate changes. The study employed two research designs namely a case study and a cross sectional survey. Hence, a combination of tools including Focus Group Discussions (FGDs), key informant interviews and semi-structured questionnaires, were used . for data collection. The research .findings showed that farmers possess a wide range of indigenous knowledge on agro-biodiversity which they use in adapting to climatic changes. The type of indigenous knowledge identified include those on soil characteristics, soil . fertility and infertility, cropping systems, seed storage and use of wild food products. It was recommended that such indigenous knowledge be promoted and used in other similar localities to foster the farmers' ability to adapt to climate changes.