Research Article published by Elsevier Volume 132, Issue 3, 18 December 2008
An effective therapeutic regimen is available for the treatment of tuberculosis (TB), however in developing countries; patient non-compliance due to high dose frequency and the lengthy duration of treatment, presents a major challenge, thus resulting in treatment failure. To address this challenge, the project seeks to develop a nano-drug delivery system whereby anti-TB drugs can be administered in a single dose that maintains an active level of the drug for at least one week.