dc.creator | Nyandoro, Stephen S. | |
dc.creator | Mdachi, Stephen | |
dc.creator | Nkunya, Mayunga H. H. | |
dc.creator | Irungu, Beatrice N. | |
dc.creator | Moshi, Mainen | |
dc.creator | Moulton, Brian | |
dc.creator | Luisi, Brian S. | |
dc.date | 2016-06-26T17:08:46Z | |
dc.date | 2016-06-26T17:08:46Z | |
dc.date | 2007-01 | |
dc.date.accessioned | 2018-03-27T08:54:42Z | |
dc.date.available | 2018-03-27T08:54:42Z | |
dc.identifier | http://hdl.handle.net/20.500.11810/2670 | |
dc.identifier.uri | http://hdl.handle.net/20.500.11810/2670 | |
dc.description | (-)-5-Acetoxy-6-(1-benzoyloxy-2-acetoxyethyl)-pyr-3-en-2-one (cleistenolide) and (-)-2, 6-diacetoxy-5-hydroxy-cyclohex-3-enylidenemethyl benzoate (cleistodienol) were isolated as novel antimicrobial and cytotoxic constituents of Cleistochlamys kirkii (Annonaceae), together with (Z)-(+)-5-(2, 3-dihydroxy-propylidene)-5H-furan-2-one and its acetyl and benzoyl derivatives, (-)-1, 6-desoxy-β-senepoxide, pinocembrin and polycarpol. Structural determination was achieved based on spectroscopic and other physical data. The structure of cleistenolide was confirmed by single crystal X-ray crystallographic analysis. | |
dc.language | en | |
dc.title | Cleistenolide and cleistodienol: Novel bioactive constituents of Cleistochlamys kirkii | |
dc.type | Other |
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