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Facile Synthesis of Acacetin-7-O-β-d-Galactopyranoside

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dc.creator Zacharia, James T.
dc.creator Hayashi, Masahiko
dc.date 2016-09-21T13:42:14Z
dc.date 2016-09-21T13:42:14Z
dc.date 2011-12
dc.date.accessioned 2018-03-27T08:55:01Z
dc.date.available 2018-03-27T08:55:01Z
dc.identifier Zacharia, J.T. and Hayashi, M., 2012. Facile synthesis of acacetin-7-O-β-D-galactopyranoside. Carbohydrate research, 348, pp.91-94.
dc.identifier http://hdl.handle.net/20.500.11810/3977
dc.identifier 10.1016/j.carres.2011.11.015
dc.identifier.uri http://hdl.handle.net/20.500.11810/3977
dc.description Full text can be accessed at http://www.sciencedirect.com/science/article/pii/S0008621511005714
dc.description Acacetin-7-O-β-d-galactopyranoside (1), a natural flavonoid isolated from flower heads of Chrysanthemum morifolium, has been reported to inhibit the replication of HIV in H9 cells. We achieved the total synthesis of compound 1 by employing a one-pot synthesis of the aglycon. The key reactions in this approach include the modified Baker–Venkataraman reaction and regio- and stereoselective O-glycosylations.
dc.language en
dc.title Facile Synthesis of Acacetin-7-O-β-d-Galactopyranoside
dc.type Journal Article


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